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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function.
Foskolou IP, Cunha PP, Sánchez-López E, Minogue EA, Nicolet BP, Guislain A, Jorgensen C, Kostidis S, Zandhuis ND, Barbieri L, Bargiela D, Nathanael D, Tyrakis PA, Palazon A, Giera M, Wolkers MC, Johnson RS. Foskolou IP, et al. Among authors: zandhuis nd. Cell Rep. 2023 Sep 26;42(9):113013. doi: 10.1016/j.celrep.2023.113013. Epub 2023 Aug 24. Cell Rep. 2023. PMID: 37632752 Free article.
BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis.
Imianowski CJ, Whiteside SK, Lozano T, Evans AC, Benson JD, Courreges CJF, Sadiyah F, Lau CM, Zandhuis ND, Grant FM, Schuijs MJ, Vardaka P, Kuo P, Soilleux EJ, Yang J, Sun JC, Kurosaki T, Okkenhaug K, Halim TYF, Roychoudhuri R. Imianowski CJ, et al. Among authors: zandhuis nd. J Exp Med. 2022 Dec 5;219(12):e20211476. doi: 10.1084/jem.20211476. Epub 2022 Sep 30. J Exp Med. 2022. PMID: 36178457 Free PMC article.